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HSPB8, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89117614 Shop All Abnova Corporation Products
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89-117-614 100 μL
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Catalog No. 89-117-614 Supplier Abnova Corporation Supplier No. PAB15424
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Description

Rabbit polyclonal antibody raised against HSPB8.

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq

Specifications

Antigen HSPB8
Applications Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against HSPB8.
Dilution Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In antiserum
Gene HSPB8
Gene Alias CMT2L/DHMN2/E2IG1/H11/HMN2/HMN2A/HSP22
Gene Symbols HSPB8
Host Species Rabbit
Immunogen Human HSPB8.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26353
Test Specificity Detects ∼22KDa. Does not cross-react with Hsp27 or alpha-crystallin.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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