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HTR1B Rabbit anti-Bovine, Dog, Guinea pig, Hamster, Human, Mouse, Pig, Rabbit, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89127150 Shop All Abnova Corporation Products
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50 μg
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89-127-150 50 μg
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Catalog No. 89-127-150 Supplier Abnova Corporation Supplier No. PAB25536

Description

Rabbit polyclonal antibody raised against synthetic peptide of HTR1B.

The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of 4 main groups, 5-HT-1, 5-HT-2, 5-HT-3, and 5-HT4, subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM

Specifications

Antigen HTR1B
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of HTR1B.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (7 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene HTR1B
Gene Alias 5-HT1B/5-HT1DB/HTR1D2/HTR1DB/S12
Gene Symbols HTR1B
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids at 3rd cytoplasmic domain of human HTR1B.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3351
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Bovine, Canine, Guinea Pig, Hamster, Human, Mouse, Pig, Rabbit, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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