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IAPP Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89114904 Shop All Abnova Corporation Products
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89-114-904 100 μL
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Catalog No. 89-114-904 Supplier Abnova Corporation Supplier No. PAB11183

Description

Rabbit polyclonal antibody raised against synthetic peptide of IAPP.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]

Specifications

Antigen IAPP
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of IAPP.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:200) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene IAPP
Gene Alias AMYLIN/DAP/IAP
Gene Symbols IAPP
Host Species Rabbit
Immunogen A synthetic peptide corresponding to N-terminus of human IAPP.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3375
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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