IAPP Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-490	100 μL

Catalog No. 89-126-490 Supplier Abnova Corporation Supplier No. PAB24819

Description

Rabbit polyclonal antibody raised against synthetic peptide of IAPP.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]

Specifications

• Antigen: IAPP
• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of IAPP.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) Immunofluorescence (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In 1X PBS, pH 7.2 (0.05% sodium azide)
• Gene: IAPP
• Gene Alias: AMYLIN/DAP/IAP
• Gene Symbols: IAPP
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to IAPP.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3375
• Test Specificity: IAPP polyclonal antibody detects endogenous levels of IAPP protein.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only