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Description
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq]
Specifications
Specifications
| Antigen | IBTK |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of IBTK. |
| Dilution | ELISA (1:15000-1:65000) The optimal working dilution should be determined by the end user. |
| Formulation | In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide) |
| Gene | IBTK |
| Gene Alias | BTKI/KIAA1417/MGC142256/MGC142258/RP1-93K22.1 |
| Gene Symbols | IBTK |
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