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IGF1R Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89128302 Shop All Abnova Corporation Products
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89-128-302 100 μg
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Catalog No. 89-128-302 Supplier Abnova Corporation Supplier No. PAB26664
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Description

Rabbit polyclonal antibody raised against synthetic peptide of IGF1R.

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq

Sequence: T-D-Yp-Yp-R-K

Specifications

Antigen IGF1R
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of IGF1R.
Dilution Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (without Mg2+ and Ca2+), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene IGF1R
Gene Alias CD221/IGFIR/JTK13/MGC142170/MGC142172/MGC18216
Gene Symbols IGF1R
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding Y1165/Y1166 of human IGF1R.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3480
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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