IGF1R (phospho Y1346), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-728	100 μL

Catalog No. 89-130-728 Supplier Abnova Corporation Supplier No. PAB29290

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq

Specifications

• Antigen: IGF1R
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF1R.
• Dilution: Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: IGF1R
• Gene Alias: CD221/IGFIR/JTK13/MGC142170/MGC142172/MGC18216
• Gene Symbols: IGF1R
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1346 of human IGF1R.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3480
• Test Specificity: IGF1R (phospho Y1346) polyclonal antibody detects endogenous levels of human IGF1R only when phosphorylated at tyrosine 1346.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only