IGF2R (phospho S2409), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF2R.

Supplier:  Abnova Corporation PAB29287

Catalog No. 89-130-724

Description

The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq

Specifications

• Antigen: IGF2R
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human IGF2R.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: CD222/CIMPR/M6P-R/MPR1/MPRI
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3482
• Target Species: Human, Mouse
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50∼1:100) Western Blot (1:500∼1:1000) The optimal working dilution should be determined by the end user.
• Gene: IGF2R
• Gene Symbols: IGF2R
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S2409 of human IGF2R.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: IGF2R (phospho S2409) polyclonal antibody detects endogenous levels of human IGF2R only when phosphorylated at serine 2409.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only