IL12B, Rabbit, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-832	100 μL

Catalog No. 89-126-832 Supplier Abnova Corporation Supplier No. PAB25159

Description

Rabbit polyclonal antibody raised against synthetic peptide of IL12B.

This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40kDa cytokine receptor like subunit encoded by this gene, and a 35kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and nonatopic asthma in children. [provided by RefSeq

Specifications

• Antigen: IL12B
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of IL12B.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:200) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.05% sodium azide)
• Gene: IL12B
• Gene Alias: CLMF/CLMF2/IL-12B/NKSF/NKSF2
• Gene Symbols: IL12B
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to IL12B.
• Purification Method: Affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3593
• Test Specificity: IL12B polyclonal antibody detects endogenous levels of IL12B protein.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only