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IL1B Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89118056 Shop All Abnova Corporation Products
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100 μg
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89-118-056 100 μg
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Catalog No. 89-118-056 Supplier Abnova Corporation Supplier No. PAB16157
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Description

Rabbit polyclonal antibody raised against IL1B.

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq

Specifications

Antigen IL1B
Applications ELISA, Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against IL1B.
Dilution ELISA (1-2 ug/mL) Western Blot (2-10 ug/mL) Immunohistochemistry (2-10 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from PBS.
Gene IL1B
Gene Alias IL-1/IL1-BETA/IL1F2
Gene Symbols IL1B
Host Species Rabbit
Immunogen Human IL1B.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3553
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with deionized water store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG
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