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Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Specifications
Specifications
| Antigen | IL1RN |
| Applications | Immunohistochemistry, Western Blot, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant IL1RN. |
| Dilution | Immunohistochemistry(1:200-1:500) Western Blot(1:200-1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide) |
| Gene | IL1RN |
| Gene Alias | ICIL-1RA/IL-1ra3/IL1F3/IL1RA/IRAP/MGC10430 |
| Gene Symbols | IL1RN |
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