IL21R Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of IL21R.

Supplier:  Abnova Corporation PAB17987

Catalog No. 89-119-593

Description

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq

Specifications

• Antigen: IL21R
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of IL21R.
• Formulation: In PBS pH 7.2 (50% glycerol, 1% BSA, 0.02% sodium azide)
• Gene Alias: MGC10967/NILR
• Host Species: Rabbit
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: human A431 cell lysates can be used as a positive control and an approximately 60 KDa band should be detected.
• Content And Storage: Store at -20°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: IL21R
• Gene Symbols: IL21R
• Immunogen: A synthetic peptide corresponding to amino acids 20-32 of human IL21R.
• Regulatory Status: RUO
• Gene ID (Entrez): 50615
• Target Species: Human
• Form: Liquid

For Research Use Only