IL21R Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-176	100 μg

Catalog No. 89-114-176 Supplier Abnova Corporation Supplier No. PAB0364

Description

Rabbit polyclonal antibody raised against synthetic peptide of IL21R.

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq

Specifications

• Antigen: IL21R
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of IL21R.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% gelatin, 0.05% sodium azide)
• Gene: IL21R
• Gene Alias: MGC10967/NILR
• Gene Symbols: IL21R
• Host Species: Rabbit
• Immunogen: A mixture of synthetic peptides corresponding to amino acids 65-80 and 505-521 of human IL21R.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 50615
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only