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Description
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq]
Specifications
Specifications
| Antigen | IL23A |
| Applications | Immunocytochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of IL23A. |
| Dilution | Western Blot (2-4 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | IL23A |
| Gene Alias | IL-23/IL-23A/IL23P19/MGC79388/P19/SGRF |
| Gene Symbols | IL23A |
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