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IL4R Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89119964 Shop All Abnova Corporation Products
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100 μg
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89-119-964 100 μg
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Catalog No. 89-119-964 Supplier Abnova Corporation Supplier No. PAB18400
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Description

Rabbit polyclonal antibody raised against synthetic peptide of IL4R.

This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq

Specifications

Antigen IL4R
Applications ELISA, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of IL4R.
Dilution Western Blot (1:500-1:1000) Immunofluorescence (1:500-1:1000) ELISA (1:5000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene IL4R
Gene Alias CD124/IL4RA
Gene Symbols IL4R
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding Y497 of human IL4R.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3566
Test Specificity This antibody is specific to IL4R.
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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