IL6ST, Rabbit, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of IL6ST.
Manufacturer: Abnova Corporation PAB18317
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
|Rabbit polyclonal antibody raised against synthetic peptide of IL6ST.|
|In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)|
|A synthetic peptide corresponding to residues surrounding S782 of human IL6ST.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody is specific to IL6ST.|
|ELISA, Immunohistochemistry, Western Blot|
|Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:60000) The optimal working dilution should be determined by the end user.|
For Research Use Only