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  6. 89119883

IL6ST, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89119883 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-119-883 100 μg
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Catalog No. 89-119-883 Supplier Abnova Corporation Supplier No. PAB18317
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Description

Rabbit polyclonal antibody raised against synthetic peptide of IL6ST.

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq

Specifications

Antigen IL6ST
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of IL6ST.
Dilution Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:60000) The optimal working dilution should be determined by the end user.
Formulation In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
Gene IL6ST
Gene Alias CD130/CDw130/GP130/GP130-RAPS/IL6R-beta
Gene Symbols IL6ST
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues surrounding S782 of human IL6ST.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3572
Test Specificity This antibody is specific to IL6ST.
Target Species Human, Mouse
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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