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Description
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq
Specifications
Specifications
| Antigen | IL7 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Biotin |
| Description | Rabbit polyclonal antibody raised against full length recombinant IL7. |
| Dilution | ELISA (1:20000-1:100000) Western Blot (1:2000-1:10000) The optimal working dilution should be determined by the end user. |
| Formulation | Lyophilized from 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide) |
| Gene | IL7 |
| Gene Alias | IL-7 |
| Gene Symbols | IL7 |
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