ILF3 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-044	100 μL

Catalog No. 89-130-044 Supplier Abnova Corporation Supplier No. PAB28534

Description

Rabbit polyclonal antibody raised against recombinant ILF3.

This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45kDa and 90kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms

Sequence: VMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSEQAESDNMDVPPEDDSKEGAGEQKTEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTALLDKVADNLAIQLAAVTEDKYEILQSVDDAAIVIK

Specifications

• Antigen: ILF3
• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against recombinant ILF3.
• Dilution: Western Blot (1:100-1:500) Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
• Gene: ILF3
• Gene Alias: CBTF/DRBF/DRBP76/MMP4/MPHOSPH4/MPP4/NF-AT-90/NF110/NF90/NFAR/NFAR-1/NFAR2/TCP110/TCP80
• Gene Symbols: ILF3
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to amino acids of human ILF3.
• Purification Method: Antigen affinity purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3609
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG

For Research Use Only