ILK (phospho S246), Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-130-739	100 μL

Catalog No. 89-130-739 Supplier Abnova Corporation Supplier No. PAB29300

Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human ILK.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

Specifications

• Antigen: ILK
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human ILK.
• Dilution: Immunohistochemistry (1:50∼1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene: ILK
• Gene Alias: DKFZp686F1765/P59
• Gene Symbols: ILK
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S246 of human ILK.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3611
• Test Specificity: ILK (phospho S246) polyclonal antibody detects endogenous levels of human ILK only when phosphorylated at serine 246.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only