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INPP5D, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89115357 Shop All Abnova Corporation Products
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89-115-357 100 μL
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Catalog No. 89-115-357 Supplier Abnova Corporation Supplier No. PAB11753

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Rabbit polyclonal antibody raised against synthetic peptide of INPP5D.

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Specifications

Antigen INPP5D
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Concentration Lot specific
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of INPP5D.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Gene INPP5D
Gene Alias MGC104855/MGC142140/MGC142142/SHIP/SHIP1/SIP-145/hp51CN
Gene Symbols INPP5D
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus of human INPP5D.
Purification Method Immunoaffinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3635
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
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For Research Use Only

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