INS Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-131-711	150 μg

Catalog No. 89-131-711 Supplier Abnova Corporation Supplier No. PAB5058

Description

Rabbit polyclonal antibody raised against synthetic peptide of INS.

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]

Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ

Specifications

• Antigen: INS
• Applications: ELISA, Immunoprecipitation
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of INS.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.5 (50% glycerol, 0.01% thimerosal)
• Gene: INS
• Gene Alias: ILPR/IRDN
• Gene Symbols: INS
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 33-63 of human INS.
• Quantity: 150 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3630
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only