Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 07169IMI

MilliporeSigma™ Rabbit anti-iPLA2, Polyclonal,

Catalog No. 07169IMI Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
07-169-IMI 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 07-169-IMI Supplier MilliporeSigma™ Supplier No. 07169I
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Specifically detects iPLA2 in Human samples, and it is validated for Immunohistochemistry, Western Blotting

Phospholipase A2 (PLA2) enzymes constitute the largest class of phospholipases, members of which catalyze the hydrolysis of the phospholipid sn-2 ester bond, generating a free fatty acid and a lysophospholipid. PLA2 enzymes are divided into 14 groups (I-XIV), including 20 subgroups (e.g. IA, IB, VIA-1, VIA-2, VIB, etc.), based on sequence homology. Historically, PLA2 enzymes have also been classified based on their biological characteristics into three types, secretory (sPLA2), cytosolic Ca2+-dependent (cPLA2), and cytosolic Ca2+-independent (iPLA2), when sequence data were not available. (PMID 12401193 & 12694560). Anti-iPLA2, is a purified rabbit polyclonal raised against immunogen sequence present in the group VI SH-iPLA2 & LH-iPLA2 (85/88kDa calcium-independent phospholipase A2) isoforms, but not found in the 53.2kDa Ankyrin-iPLA2-1 and 46.5kDa Ankyrin-iPLA2-2 splice variants encoded by the same PLA2G6 (PLPLA9) gene (UniProt O60733). Immunogen sequence is 100% conserved in murine (NP_058611.1) and rodent (AAC53136.1) species.
TRUSTED_SUSTAINABILITY

Specifications

Antigen iPLA2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Formulation Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No. O60733
Gene Symbols PLA2G6; PLPLA9
Host Species Rabbit
Immunogen KLH-conjugated linear peptide corresponding to human iPLA2 near the C-terminal.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Gene ID (Entrez) NP_001186491
Target Species Human
Content And Storage Stable for one year at 2°C to 8°C from date of receipt.
Show More Show Less

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.