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ITGB4 (phospho Y1526), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89133495 Shop All Abnova Corporation Products
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89-133-495 100 μL
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Catalog No. 89-133-495 Supplier Abnova Corporation Supplier No. PAB7916
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of ITGB4.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen ITGB4
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of ITGB4.
Dilution ELISA (1:2000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
Gene ITGB4
Gene Alias CD104
Gene Symbols ITGB4
Host Species Rabbit
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1526 of human ITGB4.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3691
Test Specificity This peptide sequence is found in all three integrin-b4 isoforms and is highly conserved in rat and mouse integrin-b4.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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