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KCNN2, Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89129259 Shop All Abnova Corporation Products
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50 μg
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89-129-259 50 μg
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Catalog No. 89-129-259 Supplier Abnova Corporation Supplier No. PAB27742
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Description

Rabbit polyclonal antibody raised against synthetic peptide of KCNN2.

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen KCNN2
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of KCNN2.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene KCNN2
Gene Alias KCa2.2/SK2/SKCA2/hSK2
Gene Symbols KCNN2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 18 amino acid at C-terminus of human KCNN2.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3781
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Target Species Human, Monkey
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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