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KDR (phospho Y951), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89115982 Shop All Abnova Corporation Products
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100 μg
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89-115-982 100 μg
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Catalog No. 89-115-982 Supplier Abnova Corporation Supplier No. PAB12648
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of KDR.

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq

Sequence: KDYVG

Specifications

Antigen KDR
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of KDR.
Dilution Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) Immunohistochemistry (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In TBS, pH 7.2 (BSA, 10% Proclin300)
Gene KDR
Gene Alias CD309/FLK1/VEGFR/VEGFR2
Gene Symbols KDR
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding Y951 of human KDR.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3791
Test Specificity This antibody recognizes ∼240 KDa of human KDR at a phosphorylation site of Tyrosine 951. It does not recognize non-phosphorylated peptides.
Target Species Human, Mouse
Content And Storage Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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