KDR Rabbit anti-Dog, Human, Monkey, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of KDR.

Manufacturer:  Abnova Corporation PAB16522

Catalog No. 89-118-392

Description

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq

Specifications

• Antigen: KDR
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of KDR.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: CD309/FLK1/VEGFR/VEGFR2
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 3791
• Target Species: Canine, Human, Monkey
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: KDR
• Gene Symbols: KDR
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human KDR.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Test Specificity: Internal domain of human.
• Content And Storage: Store at 4°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only