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Description
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | KREMEN1 |
| Applications | ELISA, Flow Cytometry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of KREMEN1. |
| Dilution | Western Blot (1:1000) Flow cytometry (1:10-50) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | KREMEN1 |
| Gene Alias | FLJ31863/KREMEM1/KREMEN/KRM1 |
| Gene Symbols | KREMEN1 |
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