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Description
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Specifications
Specifications
| Antigen | KRT4 |
| Applications | Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | SP210 |
| Conjugate | Unconjugated |
| Description | Rabbit monoclonal antibody raised against synthetic peptide of human KRT4. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide) |
| Gene | KRT4 |
| Gene Alias | CK4/CYK4/FLJ31692/K4 |
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