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MilliporeSigma™ Rabbit anti-Lcat, Polyclonal,

Catalog No. ABS1621MI Shop All MilliporeSigma Products
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ABS1621MI 100 μL
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Catalog No. ABS1621MI Supplier MilliporeSigma™ Supplier No. ABS1621
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Description

Rabbit Polyclonal Antibody

Specifically detects Lcat in Human, Mouse samples, and it is validated for Western Blotting

Phosphatidylcholine-sterol acyltransferase (EC 2.3.1.43; UniProt P16301; also known as Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase, LCAT) is encoded by the Lcat (also known as AI046659; D8Wsu61e) gene (Gene ID 16816) in murine species. LCAT catalyzes the esterification of cholesterol and phosphatidylcholines (PCs) to cholesteryl esters and lysoPCs on the surface of high and low density lipoproteins (HDLs and LDLs). LCAT reaction is essential for the maturation of nascent HDL particles in plasma, and a genetic deficiency of LCAT results in the near absence of normal HDL particles and the presence of plasma very low density and low density lipoprotein particles of abnormal size and shape. LCAT is initially produced with a 24-aa N-terminal signal peptide, which is later cleaved to form the mature enzyme. LCAT is synthesized in the liver before it is secreted into the plasma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lcat
Applications Western Blot
Classification Polyclonal
Formulation Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No. P16301
Gene Symbols Lcat
Host Species Rabbit
Immunogen Recombinant protein corresponding to mouse Lcat.
Purification Method Unpurified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Gene ID (Entrez) NP_032516
Target Species Human, Mouse
Content And Storage Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Form Serum
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For Research Use Only

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