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LCK (phospho Y505), Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89116071 Shop All Abnova Corporation Products
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100 μg
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89-116-071 100 μg
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Catalog No. 89-116-071 Supplier Abnova Corporation Supplier No. PAB12750
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Description

Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Specifications

Antigen LCK
Applications ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.
Dilution Western Blot (0.1-1 ug/mL) ELISA (0.01-0.1 ug/mL) Immunoprecipitation (2-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In TBS, pH 7.2 (BSA, 10% Proclin300)
Gene LCK
Gene Alias YT16/p56lck/pp58lck
Gene Symbols LCK
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding Y505 of human, rat, bovine and dog LCK.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3932
Test Specificity This antibody recognizes LCK with a phosphorylated site of Tyrosine 505. It does not cross-react with non-phosphospecific peptide.
Target Species Bovine, Canine, Human, Mouse, Rat
Content And Storage Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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