LCK (phospho Y394), Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.

Supplier:  Abnova Corporation PAB12169

Catalog No. 89-115-664

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Sequence: NEYpTA

Specifications

• Antigen: LCK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
• Gene: LCK
• Gene Symbols: LCK
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y394 of human LCK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: Lck (phospho-Tyr393) antibody detects endogenous levels of Lck only when phosphorylated at tyrosine 393.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: Western Blot
• Concentration: 1 mg/mL
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of LCK.
• Formulation: In PBS (without Mg²⁺ and Ca²⁺), 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
• Gene Alias: YT16/p56lck/pp58lck
• Host Species: Rabbit
• Purification Method: Immunoaffinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 3932
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only