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Description
This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription. [provided by RefSeq
Specifications
Specifications
| Antigen | LONP1 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against recombinant LONP1. |
| Dilution | Western Blot (Human: 1:100-1:250, Mouse/Rat: 1:100-1:500 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide) |
| Gene | LONP1 |
| Gene Alias | LON/LONP/LonHS/MGC1498/PIM1/PRSS15/hLON |
| Gene Symbols | LONP1 |
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