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LPHN1 Rabbit anti-Hamster, Human, Monkey, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89128172 Shop All Abnova Corporation Products
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50 μg
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89-128-172 50 μg
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Catalog No. 89-128-172 Supplier Abnova Corporation Supplier No. PAB26533

Description

Rabbit polyclonal antibody raised against synthetic peptide of LPHN1.

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with nonhuman species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being noncovalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms

Specifications

Antigen LPHN1
Applications Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of LPHN1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene LPHN1
Gene Alias CIRL1/CL1/LEC2
Gene Symbols LPHN1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 16 amino acids at C-terminus of human LPHN1.
Purification Method Immunoaffinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22859
Test Specificity BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NOL6 (50%).
Target Species Hamster, Human, Monkey, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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