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LRP6 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89131545 Shop All Abnova Corporation Products
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400 μL
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89-131-545 400 μL
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Catalog No. 89-131-545 Supplier Abnova Corporation Supplier No. PAB4736
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Description

Rabbit polyclonal antibody raised against synthetic peptide of LRP6.

The LRP6 gene encodes a member of the low density lipoprotein receptor (LDLR) gene family, which consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDLR proteins are comprised of the same basic structural motifs: an extracellular domain that contains LDLR binding repeats and EGF repeats with associated spacer domains containing the YWTD motif; a single transmembrane-spanning domain; and a C-terminal cytoplasmic domain that generally contains at least 1 copy of the NPXY motif (Brown et al., 1998 [PubMed 9704021]). LRP6 and LRP5 (MIM 603506) function as coreceptors for WNT (MIM 164820) ligands and thus play a role in WNT signaling, which is important in a wide variety of biologic processes during pre- and postnatal life in invertebrates and vertebrates (Kokubu et al., 2004 [PubMed 15469977]).[supplied by OMIM

Specifications

Antigen LRP6
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of LRP6.
Dilution ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:10-50) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene LRP6
Gene Alias ADCAD2/FLJ90062/FLJ90421
Gene Symbols LRP6
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human LRP6.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4040
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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