LTB Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of LTB.
Manufacturer: Abnova Corporation PAB17378
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
|Western Blot (1:500-1:1000) Immunofluorescence (1:500-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody detects endogenous levels of total LTB protein.|
|Immunofluorescence, Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of LTB.|
|In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)|
|A synthetic peptide corresponding to C-terminus of human LTB.|
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