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Description
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM
Specifications
Specifications
| Antigen | MACC1 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of MACC1. |
| Dilution | Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.02% sodium azide) |
| Gene | MACC1 |
| Gene Alias | 7A5/SH3BP4L |
| Gene Symbols | MACC1 |
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For Research Use Only
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