MilliporeSigma™ Rabbit anti-MACC1, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABC447

Catalog No. ABC447MI

Description

Specifically detects MACC1 in Human samples, and it is validated for Immunohistochemistry, Western Blotting

Metastasis-associated in colon cancer protein 1 (UniProt Q6ZN28; also known as Putative binding protein 7a5, SH3 domain-containing protein 7a5) is encoded by the MACC1 gene (also known as 7A5, SH3BP4L) (Gene ID 346389) in human. MACC1 is an oncogenic transcription activator that was initially detected in colon cancer. Ongoing studies also establish a strong association between MACC1 upregulation and tumor metastasis, progression, and poor prognosis in many other types of cancers, including cervical cancer, epithelial ovarian cancer, hepatocellular carcinoma, rectal cancer, pancreatic cancer, lung cancer, nasopharyngeal carcinoma, breast cancer, osteosarcoma, glioma, esophageal cancer, gastric cancer, and in non-small cell lung cancer (NSCLC).

Specifications

• Antigen: MACC1
• Classification: Polyclonal
• Gene Accession No.: Q6ZN28
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human

• Applications: Immunohistochemistry, Western Blot
• Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: MACC1
• Immunogen: GST-tagged recombinant protein corresponding to the C-terminus of human MACC1.
• Quantity: 100 μg
• Research Discipline: Apoptosis, Cancer
• Gene ID (Entrez): NP_877439
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only