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MilliporeSigma™ Rabbit anti-MACC1, Polyclonal,
Rabbit Polyclonal Antibody
Supplier: MilliporeSigma™ ABC447
Description
Specifically detects MACC1 in Human samples, and it is validated for Immunohistochemistry, Western Blotting
Metastasis-associated in colon cancer protein 1 (UniProt Q6ZN28; also known as Putative binding protein 7a5, SH3 domain-containing protein 7a5) is encoded by the MACC1 gene (also known as 7A5, SH3BP4L) (Gene ID 346389) in human. MACC1 is an oncogenic transcription activator that was initially detected in colon cancer. Ongoing studies also establish a strong association between MACC1 upregulation and tumor metastasis, progression, and poor prognosis in many other types of cancers, including cervical cancer, epithelial ovarian cancer, hepatocellular carcinoma, rectal cancer, pancreatic cancer, lung cancer, nasopharyngeal carcinoma, breast cancer, osteosarcoma, glioma, esophageal cancer, gastric cancer, and in non-small cell lung cancer (NSCLC).
Specifications
MACC1 | |
Polyclonal | |
Q6ZN28 | |
Rabbit | |
Affinity Purified | |
RUO | |
Primary | |
Human |
Immunohistochemistry, Western Blot | |
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide. | |
MACC1 | |
GST-tagged recombinant protein corresponding to the C-terminus of human MACC1. | |
100 μg | |
Apoptosis, Cancer | |
NP_877439 | |
Stable for one year at 2°C to 8°C from date of receipt. |
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Product Title
For Research Use Only
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