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MilliporeSigma™ Rabbit anti-MACC1, Polyclonal,

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ ABC447

Catalog No. ABC447MI


Description

Description

Specifically detects MACC1 in Human samples, and it is validated for Immunohistochemistry, Western Blotting

Metastasis-associated in colon cancer protein 1 (UniProt Q6ZN28; also known as Putative binding protein 7a5, SH3 domain-containing protein 7a5) is encoded by the MACC1 gene (also known as 7A5, SH3BP4L) (Gene ID 346389) in human. MACC1 is an oncogenic transcription activator that was initially detected in colon cancer. Ongoing studies also establish a strong association between MACC1 upregulation and tumor metastasis, progression, and poor prognosis in many other types of cancers, including cervical cancer, epithelial ovarian cancer, hepatocellular carcinoma, rectal cancer, pancreatic cancer, lung cancer, nasopharyngeal carcinoma, breast cancer, osteosarcoma, glioma, esophageal cancer, gastric cancer, and in non-small cell lung cancer (NSCLC).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MACC1
Polyclonal
Q6ZN28
Rabbit
Affinity Purified
RUO
Primary
Human
Immunohistochemistry, Western Blot
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
MACC1
GST-tagged recombinant protein corresponding to the C-terminus of human MACC1.
100 μg
Apoptosis, Cancer
NP_877439
Stable for one year at 2°C to 8°C from date of receipt.
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