MAP2K7 (phospho S271), Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MAP2K7.

Supplier:  Abnova Corporation PAB29211

Catalog No. 89-130-645

Description

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq

Specifications

• Antigen: MAP2K7
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic phosphopeptide of human MAP2K7.
• Formulation: In PBS, pH 7.4 (without Mg²⁺ and Ca²⁺), (50% glycerol, 0.02% sodium azide)
• Gene Alias: Jnkk2/MAPKK7/MKK7/PRKMK7
• Host Species: Rabbit
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5609
• Target Species: Human, Mouse, Rat
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: Immunohistochemistry (1:50-1:100) Western Blot (1:500-1000) The optimal working dilution should be determined by the end user.
• Gene: MAP2K7
• Gene Symbols: MAP2K7
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S271 of human MAP2K7.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody detects endogenous levels of MAP2K7 only when phosphorylated at serine 271.
• Content And Storage: Store at -20°C.
  Avoid repeated freezing and thawing.

For Research Use Only