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MAP4K4, Rabbit, Clone: SP177, Abnova™

Catalog No. 89109389 Shop All Abnova Corporation Products
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89-109-389 100 μL
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Catalog No. 89-109-389 Supplier Abnova Corporation Supplier No. MAB11219

Description

Rabbit monoclonal antibody raised against synthetic peptide of MAP4K4.

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq

Specifications

Antigen MAP4K4
Applications Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone SP177
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against synthetic peptide of MAP4K4.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
Formulation In 10mM PBS, pH 7.6 (1% BSA, 0.09% sodium azide)
Gene MAP4K4
Gene Alias FLH21957/FLJ10410/FLJ20373/FLJ90111/HGK/KIAA0687/NIK
Gene Symbols MAP4K4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus region of human MAP4K4.
Purification Method Protein A/G purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9448
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG
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