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MAPK10 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89130477 Shop All Abnova Corporation Products
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400 μL
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89-130-477 400 μL
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Catalog No. 89-130-477 Supplier Abnova Corporation Supplier No. PAB2895
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Description

Rabbit polyclonal antibody raised against synthetic peptide of MAPK10.

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

Specifications

Antigen MAPK10
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of MAPK10.
Dilution Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene MAPK10
Gene Alias FLJ12099/FLJ33785/JNK3/JNK3A/MGC50974/PRKM10/p493F12/p54bSAPK
Gene Symbols MAPK10
Host Species Rabbit
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MAPK10.
Purification Method Protein G purification
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5602
Target Species Human, Mouse
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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