MilliporeSigma™ Rabbit anti-MATE1, Polyclonal,

Catalog No.	Quantity
ABC522MI	200 μL

Catalog No. ABC522MI Supplier MilliporeSigma™ Supplier No. ABC522

Description

Rabbit Polyclonal Antibody

Specifically detects MATE1 in Human samples, and it is validated for Western Blotting

MATE1 is part of our innate metabolism and functions as multi-substrate small molecule transporter. MATE1 is widely expressed in many tissues and is found especially found in luminal membranes of urinary tubules, bile caniculi and brush border membranes. MATE1 is the cellular transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, cephalosporin, cephalexin and cephradin, and MATE1 often mediates the final excretion step for toxic organic cations. In disease treatments, it also is the transporter for the uptake of various anti-cancer drugs like acyclovir and ganciclovir but also toxins like Paraquat (a potent herbicide).

Specifications

• Antigen: MATE1
• Applications: Western Blot
• Classification: Polyclonal
• Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: Q96FL8
• Gene Symbols: SLC47A1; MATE1
• Host Species: Rabbit
• Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human MATE1.
• Purification Method: Affinity Purified
• Quantity: 200 μL
• Regulatory Status: RUO
• Research Discipline: Apoptosis, Cancer
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_060712
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.

For Research Use Only