MBD2 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-124-047	400 μL

Catalog No. 89-124-047 Supplier Abnova Corporation Supplier No. PAB2234

Description

Rabbit polyclonal antibody raised against synthetic peptide of MBD2.

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. [provided by RefSeq

Specifications

• Antigen: MBD2
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MBD2.
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.09% sodium azide)
• Gene: MBD2
• Gene Alias: DKFZp586O0821/DMTase/NY-CO-41
• Gene Symbols: MBD2
• Host Species: Rabbit
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MBD2.
• Purification Method: Protein G purification
• Quantity: 400 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8932
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only