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Description
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response
Specifications
Specifications
| Antigen | MBTPS2 |
| Applications | ELISA, Immunofluorescence |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of MBTPS2. |
| Dilution | Immunofluorescence (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol) |
| Gene | MBTPS2 |
| Gene Alias | FLJ32174/S2P |
| Gene Symbols | MBTPS2 |
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