MDC1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MDC1.

Supplier:  Abnova Corporation PAB0366

Catalog No. 89-114-178

Description

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq

Specifications

• Antigen: MDC1
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MDC1.
• Formulation: In PBS (0.2% gelatin, 0.05% sodium azide)
• Gene Alias: DKFZp781A0122/KIAA0170/MGC166888/NFBD1
• Host Species: Rabbit
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Western Blot
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: MDC1
• Gene Symbols: MDC1
• Immunogen: A synthetic peptide corresponding to amino acids 871-888 of human MDC1.
• Regulatory Status: RUO
• Gene ID (Entrez): 9656
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only