MDC1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-114-607	100 μg

Catalog No. 89-114-607 Supplier Abnova Corporation Supplier No. PAB10074

Description

Rabbit polyclonal antibody raised against synthetic peptide of MDC1.

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq

Specifications

• Antigen: MDC1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MDC1.
• Dilution: ELISA (1:3000-1:12000) The optimal working dilution should be determined by the end user.
• Formulation: In 20mM KH₂PO₄, 150mM NaCl, pH 7.2 (0.01% sodium azide)
• Gene: MDC1
• Gene Alias: DKFZp781A0122/KIAA0170/MGC166888/NFBD1
• Gene Symbols: MDC1
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to amino acids 679-694 of human MDC1.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9656
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only