MLH3 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-119-210	100 μg

Catalog No. 89-119-210 Supplier Abnova Corporation Supplier No. PAB17549

Description

Rabbit polyclonal antibody raised against synthetic peptide of MLH3.

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq

Specifications

• Antigen: MLH3
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MLH3.
• Dilution: Western Blot (1:500-1:1000) ELISA (1:40000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
• Gene: MLH3
• Gene Alias: HNPCC7/MGC138372
• Gene Symbols: MLH3
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to internal of human MLH3.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27030
• Test Specificity: This antibody detects endogenous levels of total MLH3 protein.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only