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Description
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq
Specifications
Specifications
| Antigen | MLXIPL |
| Applications | Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against synthetic peptide of MLXIPL. |
| Dilution | Immunofluorescence (1:100-1:500) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.01% sodium azide) |
| Gene | MLXIPL |
| Gene Alias | CHREBP/MIO/MONDOB/WBSCR14/WS-bHLH/bHLHd14 |
| Gene Symbols | MLXIPL |
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