MMP11, Rabbit, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MMP11.

Supplier:  Abnova Corporation PAB4780

Catalog No. 89-131-569

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq]

Specifications

• Antigen: MMP11
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MMP11.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: SL-3/ST3/STMY3
• Host Species: Rabbit
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4320
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:1000) Western Blot (1:100-500) The optimal working dilution should be determined by the end user.
• Gene: MMP11
• Gene Symbols: MMP11
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MMP11.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Liquid

For Research Use Only