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MMP14 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Catalog No. 89120327 Shop All Abnova Corporation Products
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89-120-327 100 μg
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Catalog No. 89-120-327 Supplier Abnova Corporation Supplier No. PAB18771
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Description

Rabbit polyclonal antibody raised against synthetic peptide of MMP14.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq

Specifications

Antigen MMP14
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Rabbit polyclonal antibody raised against synthetic peptide of MMP14.
Dilution ELISA (1:10000-1:10000) Western Blot (1:200-1:500) Immunohistochemistry (1:50-1:500) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 0.02% sodium azide, 2% BSA
Gene MMP14
Gene Alias MMP-X1/MT1-MMP/MTMMP1
Gene Symbols MMP14
Host Species Rabbit
Immunogen A synthetic peptide corresponding to 14 amino acids at internal region of human MMP14.
Purification Method Peptide affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4323
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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