MMP14 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MMP14.

Manufacturer:  Abnova Corporation PAB18771

Catalog No. 89-120-327

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq

Specifications

• Antigen: MMP14
• Classification: Polyclonal
• Description: Rabbit polyclonal antibody raised against synthetic peptide of MMP14.
• Formulation: In buffer containing 0.02% sodium azide, 2% BSA
• Gene Alias: MMP-X1/MT1-MMP/MTMMP1
• Host Species: Rabbit
• Purification Method: Peptide affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4323
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000-1:10000) Western Blot (1:200-1:500) Immunohistochemistry (1:50-1:500) The optimal working dilution should be determined by the end user.
• Gene: MMP14
• Gene Symbols: MMP14
• Immunogen: A synthetic peptide corresponding to 14 amino acids at internal region of human MMP14.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Murine, Rat

For Research Use Only