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MMP14 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Rabbit polyclonal antibody raised against synthetic peptide of MMP14.

Manufacturer:  Abnova Corporation PAB18771

Catalog No. 89-120-327



Description

Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq

Specifications

Specifications

MMP14
Polyclonal
Rabbit polyclonal antibody raised against synthetic peptide of MMP14.
In buffer containing 0.02% sodium azide, 2% BSA
MMP-X1/MT1-MMP/MTMMP1
Rabbit
Peptide affinity purification
RUO
4323
Liquid
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
ELISA (1:10000-1:10000) Western Blot (1:200-1:500) Immunohistochemistry (1:50-1:500) The optimal working dilution should be determined by the end user.
MMP14
MMP14
A synthetic peptide corresponding to 14 amino acids at internal region of human MMP14.
100 μg
Primary
Human, Murine, Rat
Safety and Handling

Safety and Handling

SDS
Documents
Product Certifications
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