MMP14 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova
Rabbit polyclonal antibody raised against synthetic peptide of MMP14.
Manufacturer: Abnova Corporation PAB18771
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq
|ELISA (1:10000-1:10000) Western Blot (1:200-1:500) Immunohistochemistry (1:50-1:500) The optimal working dilution should be determined by the end user.|
|Peptide affinity purification|
|ELISA, Immunohistochemistry (PFA fixed), Western Blot|
|Rabbit polyclonal antibody raised against synthetic peptide of MMP14.|
|In buffer containing 0.02% sodium azide, 2% BSA|
|A synthetic peptide corresponding to 14 amino acids at internal region of human MMP14.|
|Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Human, Murine, Rat|
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