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MMP2 Rabbit, Polyclonal Antibody, Abnova™

Catalog No. 89120650 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-120-650 100 μg
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Catalog No. 89-120-650 Supplier Abnova Corporation Supplier No. PAB19119

Description

Rabbit polyclonal antibody raised against synthetic peptide of MMP2.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen MMP2
Applications Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Formulation Lyophilized from 0.9mg NaCl, 0.2mg Na2HPO4 (5mg BSA, 0.05mg sodium azide, 0.05mg Thimerosal)
Gene MMP2
Gene Alias CLG4, CLG4A, MMP-II, MONA, TBE-1
Gene Symbols MMP2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to amino acids at N-terminus of human MMP2.
Purification Method Affinity Purified
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4313
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 200μL of deionized water to a concentration of 500μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Isotype IgG
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